Pro.Xuemei Zhou engaged in public transportation system planning design and service, intelligent transportation system technology and method, the comprehensive transportation system and multimodal transport hub and the theories and methods such as the direction of the research, especially based on traffic engineering and system engineering theory and information technology, the research "bus service operation" problems and countermeasures. The research results are as follows:

She has completed one project of the National Natural Science Foundation of China, one project of the National Railway Administration, one project of the National Railway Administration. I have participated in a number of national projects, such as the national 973 Program sub-topic, the National key scientific and technological research projects of the Tenth Five-year Plan, the National 863 Program, the General and youth funds of the National Natural Science Foundation of China, etc. Also hosted and participated in Zhongshan, Zhuhai, Xiamen, Longyan, Liuzhou, Tianjin, Beijing, Shanghai, Ganzhou, Cixi, Jiangyin, Suzhou, Jinan, Zibo, Jiamusi, Qitaihe, Qinhuangdao, Urumqi, Jiujiang city, local government and scientific research institutes of the comprehensive traffic planning and design of integrated transport hub and comprehensive development, rail transit planning, public transportation system planning, etc and consulting topics more than 30.

She has won the third prize of Science and Technology Progress of Shanghai, the third prize of Science and Technology progress of Guangxi, the first prize of Excellent Engineering consultation of Tianjin Engineering Consultation Association, and the second prize of Shandong Provincial Public Security Department. He has published more than 90 academic papers related to integrated transportation hub, public transportation and intelligent transportation system, among which 17 papers were indexed by SCI and 25 papers were indexed by EI.

She is  also a bidding evaluation expert of Shanghai Municipal Government, a member of Shanghai Transportation Engineering Society and a member of Shanghai System Simulation Society. The journal reviewer of China journal of highway, journal of southeast university in English journal, journal of south China university of technology, Beijing university of technology, transportation engineering journal, journal of Shandong university, highway traffic science and technology, journal of Shanghai university of science and technology, control, and decision-making, journal of Qingdao university, journal of Chongqing Jiaotong university, Guilin university of technology, Lanzhou university of technology journal, journal of Guangxi university, Physica A: Statistical Mechanics and its Applications; Journal of Urban Planning and Development; Sustainability; Journal of Advanced Transportation; Sensors; Informatics; Energies; Infrastructures; Journal of Open Innovation: Technology, Market, and Complexity; Informatics; Mathematical Modelling of Natural Phenomena; Journal of Modern Transportation (JMTR); International Journal of Environmental Research and Public Health; World Electric Vehicle Journal; Transportation Research Interdisciplinary Perspectives.